Colchicum with gout - properties and features of use. Colchicum (autumn), planting and care - healing properties, application

Colchicum is a perennial herbaceous plant of the lily family. Stem glabrous, erect, low; in length is from 10 to 50 cm. The root is an oblong corm, it can reach three to five cm in length, the bulb is covered with dark brown scales (husk) along its entire length. Leaves oblong-lanceolate or elliptical, large, glabrous. Flowers solitary, bisexual, large, 20–25 cm long.

Depending on the type of colchicum, flowers can be colored from white to purple hue. The fruit is a rhombic or three-celled elliptical box. Colchicum blooms in late summer or autumn (until mid-October). The species difference of this plant is the fact that during the flowering period the leaves are not yet developed. Fruits and leaves appear only next year in spring period(as a rule, this happens immediately after the snow melts).

The seed ripening period is May-June. Immediately after the completion of the seed maturation period above-ground part colchicum completely dies off. Colchicum natural distribution area - southwestern regions Krasnodar Territory, Caucasus, India and territory Central Asia, Northern part Africa, everywhere it grows throughout Europe and the Mediterranean. The genus Colchicum has more than 70 species, which differ from each other in the period of flowering and seeding.

Useful properties of colchicum

All - aboveground and underground - parts of the colchicum are poisonous, but the bulb (root) and seeds are especially toxic. However, one should not forget that most of medicinal plants used both in traditional (as the main active ingredients in the manufacture of various pharmacological preparations) and in traditional medicine, is chemically poisonous plants.

Based on the positive dynamics that can be traced when using medicinal infusions, tinctures, as well as ointments, which include Colchicum, treatment plant found wide application in folk medicine. The chemical composition of fireweed corms contains: alkaloids of the heterocyclic series (colchicine, colchamine, colchicein), aromatic acids, sugars, flavonoids and glucoalcohols.

The chemical composition of colchicum seeds contains: alkaloids, resins, tannins, lipids and sugars. In folk medicine, infusion, tincture and ointment of Colchicum are used as analgesics (painkillers), antiemetics, diuretics and laxatives.

The use of colchicum

Before using any form medicinal product from colchicum to without fail you should consult a doctor, since all parts of the medicinal plant (and therefore all its dosage forms) are poisonous and uncontrolled intake, as well as an incorrect dosage medicinal product can lead to lethal outcome.

Ointment and infusion of a medicinal plant are used externally as an effective pain reliever for gout, arthritis, rheumatism and sciatica.

A tincture of fresh tubers of the plant has an effective effect on edema, rheumatism, cystitis, urolithiasis, as well as a feeling of tightness (compression, pressure) in the chest.

Colchicum infusion

Half a teaspoon of a fresh onion is poured into 500 ml of boiling water, left for 2 hours, and then filtered into clean dishes. The application should also be started with a minimum dose, subsequently it can be 7-8 ml up to six times a day. The infusion should be washed down with 200 ml of warm non-carbonated water.

Colchicum ointment

300 g of the aboveground and underground parts of the plant are finely chopped and poured with 500 ml of water, after which they are put on a boiling water bath for 30 minutes. Then the resulting infusion is filtered into a clean container and vaseline / butter is added until the desired consistency of the ointment is obtained. Store the resulting ointment in a tightly closed container in a cool place (10-15 degrees).

Colchicum rubbing

Recipe number 1. 1 part of the crushed dry tubers of the plant is poured with 12 parts of vinegar. The resulting solution is infused for 14 days, after which it is used as an anesthetic.

Recipe number 2. 1 part of crushed colchicum roots is poured with five parts of 50% ethyl alcohol, insist in a dark place for 10-14 days, after which it is used as a rubbing for various rheumatic diseases.

Colchicum flower

Colchicum flowers are solitary, large (up to 20–25 cm long), with six petals. Distinctive characteristic flowers of this medicinal plant is the fact that they are bisexual. Depending on the type of colchicum, flowers can be colored in different shades- from white to purple. The plant blooms from August to October inclusive.

In folk medicine, colchicum flowers are used in the manufacture of anesthetic ointment. The use of the ointment is indicated for arthritis, radiculitis, gout and rheumatism.

Colchicum planting

Colchicum is a perennial herbaceous plant (does not require transplantation for several years), absolutely unpretentious to growing conditions. Feels best on light (not dense), loose soils. Planting depth can vary from 10 to 20 cm (the depth directly depends on the size of the bulb). The plant reproduces by daughter bulbs (capable of reproduction on its own).

If it is necessary to plant / seat a plant, it is best to do this in the summer (during the period of time when the aerial part completely fades). When working with colchicum and caring for it, it is necessary to observe the rules of personal safety with particular care, since all parts of the plant (aboveground and underground) are poisonous, which is why it is recommended to carry out all manipulations with gloves.

Colchicum bulb

Colchicum bulb is a large corm, which can reach a diameter of 4 cm. Throughout its area, the bulb is covered with husks (black - brown scales). Each bulb ends with a long neck, which, in turn, is also covered with scales. In the spring, after a period of development of large leaves, the old bulb dies off and is replaced by a new young bulb as a result of assimilation.

Due to its unique chemical composition, the colchicum bulb has found wide application in traditional medicine recipes. Infusion, tincture and ointments, which include plant materials, are successfully used as an anesthetic, vasodilator and anti-inflammatory agent.

The chemical composition of the colchicum bulb contains such alkaloids as colhamine and colchicine, which are successfully used in the treatment of a number of oncological diseases, including malignant neoplasms on the skin, in the chest, in the lungs and in the gastrointestinal tract.

Colchicum tincture

Colchicum tincture has long been used in folk medicine as an effective analgesic and anti-inflammatory agent. The tincture is applied locally (directly to the area of ​​pain localization) and internally. However, before using medicinal tincture it is important to seek the advice of a doctor - tincture, like all other medicinal forms of the plant, is poisonous in large quantities and its improper and uncontrolled use can be fatal.

Recipe No. 1. 10 g of fresh onion (can be exchanged for plant seeds) is poured with 100 ml of 45% ethyl alcohol, after which the resulting infusion is placed in a dark place for 20 days. After this period, the infusion is filtered and colchicum is started with 1 drop per day (if side effects are not observed, the number of drops can be increased).

Recipe number 2. 1 part of the seeds is poured with 10 parts of 70% ethyl alcohol, then infused in a dark place for 14–20 days. The resulting tincture can be used both inside (15-20 drops 3 times a day) and externally (directly on the area of ​​pain localization).

Colchicum splendid

Colchicum splendid is a perennial herbaceous plant of the lily family. The stem is short, bare, develops in the spring (by summer, the aerial part of the magnificent colchicum dies off completely). The root is a large corm, covered over the entire area with black-brown scales, up to 4 cm in diameter. The leaves are large, bare, wide-oblong in shape, as well as the stem, develop in the spring season.

Flowers are bell-shaped, large (up to 5–7 cm long), bisexual. They can be colored from pale lilac to pink-purple. The fruit is a fairly large three-celled multi-seeded pod up to 5 cm in length. The aerial part of the plant dies off completely in the summer, blooms in autumn (September-October). It bears fruit in June, immediately after which the aerial part of the plant dies off. In the summer, the old bulb dies off, and a daughter corm is formed.

The natural habitat of the magnificent colchicum is the territory of Western and Eastern Transcaucasia, Ciscaucasia and the Main Caucasian Range. It grows mainly on forest edges. In folk medicine, the underground part of medicinal raw materials - corms, which are harvested in autumn period(during the flowering period of the plant), for maximum extraction of alkaloids, raw materials are processed in their raw form.

The chemical composition of the corms of Colchicum splendid contains over 20 different alkaloids, however, among this diversity organic compounds, the most valuable are two types - colchamine and colchicine. In addition, the chemical composition of medicinal raw materials is rich in sugars, sterols and aromatic acids.

In traditional medicine, in the form of solid dosage forms (tablets) and ointments, Colchicum splendid is used in complex therapy in the treatment of oncological diseases of the skin, papillomas of the respiratory tract, malignant neoplasms in the mammary glands and in the gastrointestinal tract.

Colchicum autumn

Colchicum autumn is a perennial herbaceous plant of the lily family. The leaves are wide, elongated, lanceolate in shape, develop in the spring. The flowers are large, painted in a pink-lilac hue. The fruit is an oblong-oval leathery capsule 3–5 cm long. Seeds are round, numerous, dark brown in color.

The flowering time of the autumn colchicum is the autumn period (September-October), it bears fruit in the summer period of the next year (June-July). Like most species representatives, the aerial part of the autumn colchicum in the summer completely dies off. All parts of the medicinal plant are very poisonous, so using them without consulting a doctor is extremely dangerous for the patient's health.

In medicine, the underground part of the autumn colchicum is used - the corm, which is harvested in the autumn period (the flowering period). After the medicinal raw material is removed from the ground, it is well washed under running water and cut into pieces (for maximum extraction of alkaloids).

The chemical composition of autumn colchicum corm contains two most valuable alkaloids - colchicine and colchamine, which are used in complex therapy for the treatment of oncological diseases of the skin and as an anesthetic for gout, rheumatism and sciatica.

Colchicum Colchicum

Colchicum (colchicum) is a perennial herbaceous plant of the lily family.

The fruit is a three-celled capsule, the seeds are small, numerous, rounded. Colchicum blooms from August to September inclusive. In medicine (traditional and folk), the seeds and the underground part of the medicinal plant are used. The corm and seeds, like the rest of the colchicum, are poisonous, so the independent use of medicinal infusions and ointments can be extremely negative impact on the human body, up to death.

The chemical composition of colchicum corms contains: alkaloids - colchicine and calchicein, phytosterols, sugars and aromatic acids. Due to its unique composition, healing infusions and ointments, which include the plant, are successfully used for chronic leukemia, skin cancer, malignant neoplasms in the gastrointestinal tract, gout, arthritis, arthrosis and sciatica.

Colchicum shady

Colchicum shady is a perennial herbaceous plant of the lily family. The leaves are large, linear, fleshy, leathery, narrowed towards the base, reach a length of 10–15 cm, a width of 2–3 cm. The root is a small corm that reaches a length of 3 cm and a diameter of 2 cm. Flowers large, painted in pale purple or lilac shades.

The natural distribution area of ​​the shady colchicum is the territory of Crimea. It grows mainly in forests, forest edges and clearings. characteristic feature shady colchicum, which distinguishes it from other varieties of this genus, is the early vegetation (April). Colchicum shadow is an endangered species and is listed in the Red Book. Based on this medical use healing infusions and ointments is unacceptable.

Colchicum contraindications

All plant parts of Colchicum are poisonous, so the use of ointments, infusions and tinctures from this medicinal plant is carried out only after consulting a doctor. Ointment, which includes Colchicum, is contraindicated in skin cancer III-IV degree.

All preparations of colchicum are contraindicated for use in persons with severe inhibition of the hematopoietic function of the bone marrow, as well as in diarrhea and diabetes. Contraindicated in children, pregnant women and women during breastfeeding.

Botanical characteristic

Colchicum autumn, translated - Colhicum autumnale, it is a small perennial corm plant. Its height varies from eight to twenty-five centimeters.

The corm is usually ovoid, up to six centimeters long, it is surrounded by dense leathery shells, dark brown in color, slightly elongated from above into a long neck. The stem of the plant is underground, rather shortened.

There are usually three or four leaves, they are elongated - lanceolate, flat, with parallel veins, their width varies from two to five centimeters. The flowers are located on short stalks.

The flowers are regular, bisexual, usually single, rarely two or three. Perianth corolla-shaped, lilac-pink, with a slightly elongated triangular tube and with a six-part funnel-shaped limb.

The lobes of the limb are elongated - elliptical in shape, on which there are veins, usually from thirteen to twenty-one. The fruit is represented by a brown leathery box, it is elongated - oval, three-celled, and slightly pointed. The plant blooms from the beginning of the first autumn month, to Nov.

Spreading

Colchicum autumn grows in small separate groups, it can be found in the Carpathians in flood meadows, as well as along rivers, streams, it also grows near highways.

Used part

This plant uses flowers, tubers and seeds. All of the above parts contain a large number of alkaloids such as colchicine and colchamine.

Directly in its tubers there is such a substance as the flavonoid apigenin, there are also some organic acids, phytosterols, as well as carbohydrates. The seeds are rich in fats, resins, sugars and tannins.

Collection and preparation

It is necessary to immediately warn readers that this plant is considered highly poisonous, therefore, it is recommended to exercise maximum caution when assembling, drying, and storing it. Corms are harvested before the flowering of autumn colchicum begins.

They are carefully released from the aerial part, removed root system, cleaned from the soil. After that, they are either used fresh or they begin the drying process, for this it is recommended to cut them into small pieces.

Then they are placed on pallets and placed in a sunny, ventilated place, or they are placed in a heated oven, where they will dry out much faster. It is not worth washing corms before harvesting, as excessive moisture can significantly reduce the quality of raw materials.

Seeds are harvested at the time when they are fully ripe. They are dried in a warm, preferably dark place, while they are placed on a cloth, scattering quite a bit. thin layer so that they reach the required condition as soon as possible.

The shelf life of finished raw materials is twelve months, and fresh corms are only suitable for ninety days. Remember that the plant is poisonous, so keep it away from children.

Application

As I mentioned earlier, the main active ingredients of this poisonous plant There are two kinds of alkaloids, namely colchamine and colchicine. They have similar therapeutic properties.

But in practice, only colchamine is used, which has a much lower toxicity, unlike colchicine. This alkaloid is a potent, effective antiblastic agent, and is used to treat oncological processes on the skin.

For example, with exophytic and endophytic forms of cancer, as well as with inoperable carcinogenic processes occurring in the esophagus, which are more often localized in its lower part.

With metastatic processes, as well as with skin cancer of the fourth and third stages, the use of colhamin is contraindicated. Do not apply calhomin ointment near the mucous membranes.

Penetrating through the skin and mucous membranes in large doses, the alkaloid colhamine can cause leukopenia, as well as others. side effects, which can be observed with its internal application.

When using the colchamine alkaloid, very often there are dyspeptic symptoms, which are expressed in the form of nausea and vomiting. With its overdose, hematopoiesis is inhibited, manifestations such as diarrhea and hair loss are possible.

If bloody impurities appear in the vomit, as well as tarry stools, it is recommended to stop taking the drug, and it is necessary to urgently carry out hemostatic therapy.

folk recipe autumn colchicum seed tincture

To prepare the tincture, you need to take the seeds of this plant, and pour them with 500 milliliters of vodka, after which it is recommended to infuse it. It is used internally as an analgesic, and is also used for deforming polyarthritis.

A local tincture prepared from the seeds can also be used and is recommended as an analgesic for gout and articular rheumatism.

Conclusion

Of course, before you start using products prepared on the basis of the autumn colchicum, it is recommended that you always consult a doctor, you should not show independence here.

Since you can harm your body by using this poisonous plant, instead of the expected benefits.

Botanical trait of colchicum

Colchicum is a perennial herbaceous plant of the lily family. The trunk is naked, erect, small; in length is from 10 to 50 cm. The root is an oblong corm, it can reach three to five cm in length, the onion is covered with dark brown scales (husks) along its entire length. Leaves oblong-lanceolate or elliptical, large, naked. The flowers are solitary, bisexual, large, reaching a length of 20–25 cm.

Depending on the type of colchicum, flowers can be painted from snow-white to purple. The fruit is a rhombic or three-celled elliptical box. Colchicum blooms in late summer or autumn (until mid-October). The species difference of this plant is the fact that during the flowering period the leaves are not yet developed. Fruits and leaves appear exclusively next year during the spring period (usually this happens immediately after the snow melts).

The seed ripening period is May-June. Immediately after the end of the seed ripening period, the aerial part of the colchicum completely dies off. The natural distribution area of ​​the colchicum is the southwestern regions of the Krasnodar Territory, the Caucasus, India and the territory of Central Asia, the northern part of Africa, everywhere it grows throughout Europe and the Mediterranean. The genus Colchicum has more than 70 species, which differ among themselves in the period of flowering and seeding.

Useful characteristics of colchicum

All - aboveground and underground - parts of the colchicum are poisonous, but the onion (root) and seeds are especially toxic. But do not forget that most of the pharmaceutical plants used both in classical (as the main active ingredients in the manufacture of various pharmacological preparations) and in traditional medicine are poisonous plants in terms of chemical composition.

Based on the positive dynamics that can be traced when using healing infusions, tinctures, and ointments, which include Colchicum, medicinal plant found extensive use in folk medicine. The chemical composition of fireweed corms contains: alkaloids of the heterocyclic series (colchicine, colchamine, colchicein), aromatic acids, sugars, flavonoids and glucoalcohols.

The chemical composition of colchicum seeds contains: alkaloids, resins, tannins, lipids and sugars. In folk medicine, colchicum infusion, tincture and ointment are used as analgesics (painkillers), antiemetics, diuretics and laxatives.

The use of colchicum

Before using any form of a pharmaceutical product from colchicum, you should definitely consult a doctor, because all parts of the pharmaceutical plant (and, as it should, all its pharmaceutical forms) are poisonous and uncontrolled intake, as well as an incorrectly selected dose of a pharmaceutical product, can lead to a fatal ending. .

Ointment and infusion of a pharmaceutical plant are used externally as an effective pain reliever for gout. arthritis, rheumatism and sciatica.

Tincture from the new tubers of the plant has an effective effect on edema, rheumatism. cystitis. urolithiasis, also with a feeling of tightness (compression, pressure) in the chest.

Colchicum infusion

Half a teaspoon of the freshest onion is poured into 500 ml of boiling water, left for 2 hours, then filtered into a clean bowl. Application should also be started with a low dose, then it can be 7-8 ml up to 6 times a day. The infusion should be washed down with 200 ml of warm non-carbonated water.

Colchicum ointment

300 g of the aboveground and underground parts of the plant are finely chopped and poured with 500 ml of water, then put in a boiling water bath for 30 minutes. Then the acquired infusion is filtered into a clean container and vaseline / butter is added until the desired mixture of ointment is obtained. Store the resulting ointment in a tightly closed container in a cold place (10-15 degrees).

Colchicum rubbing

Recipe number 1. 1 part of crushed dry tubers of the plant is poured with 12 parts of vinegar. The purchased solution is infused for 14 days, after which it is used as an anesthetic.

Recipe No. 2. 1 part of crushed colchicum roots is poured with five parts of 50% ethyl alcohol, infused in a black place for 10-14 days, after which it is used as a rubbing for various rheumatic diseases.

Colchicum flower

Colchicum flowers are solitary, large (they reach 20–25 cm in length), with six petals. hallmark The flowers of this pharmaceutical plant is the fact that they are bisexual. Depending on the type of colchicum, flowers can be painted in various colors - from snow-white to purple. The plant blooms from August to October inclusive.

In folk medicine, colchicum flowers are used in the manufacture of anesthetic ointment. The use of the ointment is indicated for arthritis. radiculitis, gout and rheumatism.

Colchicum planting

Colchicum is a perennial herbaceous plant (does not require a transplant for a couple of years), completely undemanding to growing conditions. Feels best on light (not dense), loose soils. The planting depth can vary from 10 to 20 cm (the depth directly depends on the size of the onion). The plant reproduces by daughter bulbs (capable of reproduction without the help of others).

As needed, planting / seating plants, it is best to do this in the summer (at that time gap when the aerial part completely fades). When working with colchicum and caring for it, you must carefully follow the rules of personal safety, because all parts of the plant (aboveground and underground) are poisonous, which is why it is recommended to do all manipulations with gloves.

Colchicum bulb

Colchicum bulb is a large corm, which can reach 4 cm in diameter. The bulb is covered with husks (black-brown scales) over its entire area. Each bulb ends with a long neck, which, in turn, is also covered with scales. In the spring, after a period of development big leaves, the ancient onion dies off and, as a result of assimilation, a new young onion comes to replace it.

Thanks to its unique chemical composition, Colchicum onion has found extensive use in traditional medicine recipes. Infusion, tincture and ointments, which include plant materials, are successfully used as an anesthetic, vasodilator and anti-inflammatory agent.

The chemical composition of the crocus onion contains such alkaloids as colhamine and colchicine, which are successfully used in the treatment of a number of oncological diseases, including malignant neoplasms on the skin, in the chest, in the lungs and in the gastrointestinal tract.

Colchicum tincture

Colchicum tincture has long been used in folk medicine as an effective analgesic and anti-inflammatory agent. The tincture is applied topically (specifically to the area of ​​pain localization) and internally. But before the introduction of a healing tincture, it is important to seek the advice of a doctor - the tincture, like all other pharmaceutical forms of the plant, is poisonous in large quantities and its incorrect and uncontrolled use can lead to a deadly ending.

Recipe number 1. 10 g of the freshest onion (can be exchanged for plant seeds) are poured with 100 ml of 45% ethyl alcohol, after which the purchased infusion is placed in a black place for 20 days. After this period, the infusion is filtered and colchicum is started with 1 drop per day (if no development of side effects is observed, the number of drops can be increased).

Recipe number 2. 1 part of the seeds is poured with 10 parts of 70% ethyl alcohol, then infused in a black place for 14–20 days. The purchased tincture can be used both internally (15–20 drops 3 times a day) and externally (specifically on the area of ​​pain localization).

Colchicum beautiful

Colchicum fine is a perennial herbaceous plant of the lily family. The trunk is small, naked, develops in the spring period (by summer, the aerial part of the beautiful colchicum completely dies off). The root is a large corm, covered over the entire area with black-brown scales, reaching 4 cm in diameter. The leaves are large, bare, wide-oblong in shape, as well as the trunk, develop in the spring season.

The flowers are bell-shaped, large (they reach 5–7 cm in length), bisexual. Can be dyed from soft purple to pink-purple color scheme. The fruit is a fairly large three-celled multi-seeded box up to 5 cm in length. The aerial part of the plant completely dies off in the summer, blooms in the autumn (September-October). It bears fruit in June, immediately after that the aerial part of the plant dies off. In the summer, the ancient onion dies off, with all this, a daughter corm is formed.

The natural habitat of the beautiful colchicum is the territory of Western and Eastern Transcaucasia, Ciscaucasia and the Main Caucasian Range. Grows mostly on forest edges. In folk medicine, the underground part of pharmaceutical raw materials - corms, which are harvested in the autumn (during the flowering period of the plant), has found extensive use, for the greatest extraction of alkaloids, the raw materials are processed raw.

The chemical composition of the corm of the beautiful crocus contains more than 20 different alkaloids, but among this contrast of organic compounds, two species are of the greatest value - colchamine and colchicine. In addition, the chemical composition of pharmaceutical raw materials is rich in sugars, sterols and aromatic acids.

In classical medicine, in the form of hard pharmaceutical forms (pills) and ointments, Colchicum fine is used in comprehensive therapy in the treatment of oncological diseases of the skin, papillomas of the respiratory tract, malignant neoplasms in the mammary glands and in the gastrointestinal tract.

Colchicum autumn

Colchicum autumn is a perennial herbaceous plant of the lily family. Leaves - wide, elongated, lanceolate, develop in the spring period. The flowers are large, painted in a pink-lilac color scheme. The fruit is an oblong-oval leathery box 3–5 cm long. Seeds are rounded, countless, painted in a dark brown color.

The flowering time of the autumn colchicum is the autumn period (September-October), it bears fruit in the summer period of the next year (June-July). Like most species representatives, the aerial part of the autumn colchicum in the summer period dies off one hundred percent. All parts of the pharmaceutical plant are very poisonous, so using them without consulting a doctor is very unsafe for the patient's health.

In medicine, the underground part of the autumn colchicum is used - the corm, which is harvested in the autumn period (the flowering period). After the medicinal raw material is extracted from the earth, it is perfectly washed under running water and cut into pieces (for the greatest extraction of alkaloids).

The chemical composition of autumn colchicum corm contains two most valuable alkaloids - colchicine and colchamine, which are used in the all-encompassing therapy for the treatment of oncological diseases of the skin and as an anesthetic for gout, rheumatism and sciatica.

Colchicum Colchicum

Colchicum (colchicum) is a perennial herbaceous plant of the lily family.

The fruit is a three-celled box, the seeds are small, countless, rounded. Colchicum blooms from August to September inclusive. In medicine (classical and folk), seeds and the underground part of a pharmaceutical plant are used. The corm and seeds, like other parts of colchicum, are poisonous, therefore the independent use of healing infusions and ointments can have a very negative effect on human body, straight to the deadly ending.

The chemical composition of colchicum corms contains: alkaloids - colchicine and calchicein, phytosterols, sugars and aromatic acids. Due to its unique composition, medicinal infusions and ointments, which include the plant, are successfully used for acquired leukemia, skin cancer, malignant neoplasms in the gastrointestinal tract, gout, arthritis, arthrosis and sciatica.

Colchicum shady

Colchicum shady is a perennial herbaceous plant of the lily family. The leaves are large, linear, fleshy, leathery, narrowed towards the base, reach 10–15 cm in length, 2–3 cm in width. The root is a small corm that reaches 3 cm in length and 2 cm in diameter. Flowers large, painted in pale purple or violet.

The natural distribution area of ​​the shady colchicum is the territory of Crimea. It grows mostly in forests, forest edges and clearings. The corresponding feature of the shady colchicum, which distinguishes it from other varieties of this genus, is the early vegetation (April). The shady colchicum is an endangered species and is listed in the Red Book. Based on this, honey, the introduction of medicinal infusions and ointments is unacceptable.

Colchicum contraindications

All plant parts of Colchicum are poisonous, therefore the use of ointments, infusions and tinctures from this pharmaceutical plant is carried out only after consulting a doctor. The ointment, which includes Colchicum, is contraindicated in skin cancer III-IV degree.

All preparations of colchicum are contraindicated for use in persons with severe inhibition of the hematopoietic function of the bone marrow, as well as with diarrhea and diabetes. It is contraindicated for children, pregnant women and women during breastfeeding.

Colchicum belongs to a perennial herbaceous plant species, the lily family. It is distinguished by a bare, erect, low stem, which can reach a length of up to 50 centimeters. The root of the colchicum is a corm, which has an oblong shape, can reach a length of 5 cm, is covered with dark scales on top. Brown. The leaves of the plant are large, glabrous, elliptical or oblong-lanceolate. Colchicum flowers can be single, large, bisexual, reach a length of 25 centimeters.

Description, planting and caring for colchicum

The flowers of the plant are different, they depend on the variety, they can be purple, white. The fruit of the colchicum is a rhombic or three-celled elliptical box. The plant begins to bloom in late summer or early autumn. But at the same time, his leaves are not yet fully developed. They may appear next year in the spring when the snow is completely gone.

Seeds are ready in late spring and early summer. After the seeds are completely ready, the aerial part of the plant may die off completely. Most often, the plant can be found in the Caucasus, India, Krasnodar Territory, Central Asia, North Africa. There are up to 70 varieties of plants, they bloom at different times.

Colchicum propagates with the help of daughter bulbs, it is best to plant or plant it in summer. In this case, be sure to take precautions, because the plant is poisonous, everything is best done in protective mask and gloves.

The bulb of the plant is quite large, can reach up to 4 centimeters. At the end of her long neck, which is covered with scales. In the spring, when large leaves develop, the old bulb may die off, a young bulb appears.

Due to the fact that it contains a lot useful substances, it is used in traditional medicine as a vasodilator, analgesic and anti-inflammatory agent. Can be used to cure skin cancer gastrointestinal tract, chest, lungs.

Useful properties of colchicum

Remember that the aboveground and underground parts of the plant are toxic, but the seeds and root are most poisonous. But when taking it, you need to know that almost all medicinal plants they contain toxic chemicals, so it is very important not to self-medicate, but to consult with your doctor. If you do not take into account the dosage, you can seriously poison yourself and die.

Traditional medicine uses tinctures, infusions, ointments based on colchicum. It contains such alkaloids as colchamine, colchicein, sugar, glucoalkaloids, aromatic acids, flavonoids.

Colchicum seeds are rich in resin, sugar, tannin, alkaloids. Traditional healers use all plant-based preparations as a remedy for pain, vomiting, and it also has a laxative and diuretic effect.

The use of colchicum

Infusion and ointment will help relieve pain that occurs with rheumatism, gout, sciatica.

A tincture based on fresh colchicum tubers is used to treat rheumatism, edema, if there is severe pressure in the chest area.

To prepare an infusion based on colchicum, it is tedious to take half a colchicum bulb, poly a liter of boiling water, leave everything for up to two hours. Must be applied in a small amount be sure to drink a glass warm water, purified, it should not be carbonated.

To prepare an ointment from colchicum, it is necessary to use the aboveground and underground parts of the plant, grind it first, pour half a liter of water over the floor, boil for up to half an hour. Add Vaseline to the infusion to make an ointment, be sure to store it in the refrigerator.

With severe pain during rheumatism, it is recommended to prepare a special decoction for rubbing, for it you need to take chopped dry colchicum tubers, pour vinegar. Leave up to two weeks. You can also prepare such a decoction, it will require crushed colchicum root, a fifth of alcohol, leave for 10 days, rub the places affected by rheumatism.

Useful properties of some varieties of colchicum

1. Magnificent Colchicum is characterized by a short, bare stem that appears in spring, large, broadly oblong leaves. It has large bell-shaped flowers, they can be different color, most often found in pale lilac or purple-pink. Grows in the territory of Transcaucasia. The underground part is most valued in medicine; it must be harvested in the fall. Applies this species in official medicine in the form of tablets, ointments in the treatment of skin cancer that develops in the respiratory tract, a malignant tumor in the chest, intestines and stomach.

2. Autumn colchicum has wide leaves that can be elongated, most often they appear in the spring. The flowers are large pink-lilac color. The fruit of the autumn colchicum is an oblong-oval leathery box. Seeds may be numerous, round. Traditional healers use the underground part - the corm, it is harvested early in the fall, washed thoroughly under water, cut into small pieces to extract alkaloids. With the help of this type of colchicum, you can relieve the pain that occurs with gout, rheumatism.

3. Colchicum is very poisonous, uncontrolled use of preparations based on it can lead to death. Infusions and ointments based on colchicum are used in the treatment of chronic leukemia, arthrosis, and sciatica.

4. Shady colchicum grows in the Crimea, chooses forests, glades. This species has been disappearing for a long time, therefore it is listed in the Red Book, it is strictly forbidden to use it for the manufacture of ointments and infusions.

Colchicum contraindications

Tinctures, infusions, ointments are forbidden to be used by those who have blood problems, are worried about the constant. In no case should colchicum be used by pregnant women, nursing mothers and children.

Among all types of colchicum, b. gorgeous and b. autumn. These plants are used not only in traditional medicine. On the basis of colchicum, preparations are prepared that are recommended by official pharmacology for the treatment of gout and many other diseases. When harvesting raw materials, be careful: all parts of the plant are highly poisonous!

Colchicum splendid and autumnal

Colchicum splendid (Colchicum speciosum Steven).

Description of the magnificent colchicum: family Melantievye (Autumn), (Melanthiaceae).

The plant is 20-60 cm high. The bulb is large, oblong, up to 5 cm long, 3-4 cm wide, covered with dark brown, membranous leathery shells, continuing into a long, wide tube, covering lower part stem.

Leaves 4-5 (rarely 3 or 6), broadly oblong, obtuse at the apex, 18-25 cm long, 3.5 cm wide, the lower ones are larger, ovate, up to 7 cm wide, with a long sheath covering the stem .

The flowers are large, develop in autumn in the number of 1-3, rarely 4, pink-purple or purple, petals 5-6.5 cm long, 15-22 mm wide, broadly oval or elliptical, obtuse at the top. The perianth tube is wide. The stamens are six, almost half as long as the petals. Anthers linear, 8-12 mm long, yellow. Pistil one, with three columns exceeding the stamens, thick, straight at the top, with one-sided stigma. The ovary is three-celled. The pod is three-celled, elliptical, up to 3 cm long. Seeds are round, brown, up to 2-3 mm in diameter.

Blooms in August-October. Fruits in June-July. Pollination of the flower has time to occur before frosts, and after the aerial part withers, underground, the ovules slowly develop in the ovary and the fruit begins to form. Therefore, in the spring, as soon as the sun warms up, a young fruit is taken out along with young leaves, it ripens until mid-summer.

Special signs: blooms in autumn, after the leaves have died. The base of the flowers with the ovary is in the ground. A box of seeds appears the next spring after flowering, along with leaves of a new generation. One corm can produce several flowers at the same time. The corm lives a little more than one year, a new one is formed every year.

Autumn colchicum is also allowed for use in medicine.

Autumn colchicum (Colchicum autumnale L.).

Description of autumn colchicum: family Melantievye (Autumn), (Melanthiaceae). Perennial corm plant, 8-25 cm tall.

Corm ovoid, 2.5-6 cm long, surrounded by dark brown leathery shells, elongated from above into a long neck. Stem underground, strongly shortened. Leaves, in the amount of 3 or 4, oblong-lanceolate, flat, with parallel veins, obtuse, 2-5 cm wide, disappearing by the time the plant blooms. Flowers on short stalks, regular, bisexual, single or 2-3. Perianth simple, corolla-shaped, lilac-pink, with a long trihedral tube and a funnel-shaped six-part limb; limb lobes elongated-elliptical, with 13-21 veins. The fruit is a brown leathery elongated oval sharp three-celled capsule. Blooms from September to November. The fruits ripen in June-July of the year following flowering.

Spreading: Colchicum grows in separate groups in the Krasnodar Territory, Abkhazia and the Carpathians on wet and flooded meadows along rivers, streams and highways. Noteworthy is the positive result obtained in the botanical gardens on the cultivation of colchicum in culture.

Blooming colchicum magnificent can be admired in Moscow in the Botanical Garden at VDNKh from late August to October.

Growing: unpretentious ornamental plants that develop well in sunny places. Without a transplant in one place they grow for a long time. They can be placed near bushes, high herbaceous plants but only on the south side. Prefer loose, light soils. Requires a good nutritional garden soil. The depth of planting corms depends on their size and varies from 8 to 20 cm. The distance between the bulbs is from 10 to 20 cm.

Leaves appear in early spring, collected in a near-ground rosette on a short false stem, surrounded by a sheath of the lower leaf. The plant reaches a height of 20-40 cm. A corm is formed from the lower internodes of the stem, covered with brown membranous or leathery dry covering scales, continuing with a long neck. The resulting corm has an outgrowth with a renewal bud. The old, depleted corm decomposes.

Leaves die from the end of May. You can not remove them until the bulbs ripen.

Colchicums bloom in autumn. After flowering, the seeds and fruit begin to slowly develop, hidden in a corm at the base of the flower tube. And only next spring along with the leaves, fruits appear above the soil surface. Seeds ripen by June-July next year.

Useful properties and application in traditional medicine

Parts of the plant used: tubers, seeds and flowers.

High medicinal properties Colchicum are explained by the presence of active substances in the plant. The tubers contain organic acids, phytosterols, carbohydrates; in seeds - fat, carbohydrates, resins and tannins.

AT various parts Colchicum autumn also contains:

• apigenin (choleretic and antispasmodic) - flowers;
• glucomannan (antitumor, regulator of lipid metabolism in the liver, immunoregulatory) - seeds;
• kolhamin (omain, demecolcin, colcemid) - tubers;
• colchicoside (anti-inflammatory) -club.,
• family 0.1-0.3%;
• colchicine - tubers 0.035%, flowers. 0.33% -0.51%, seeds 0.3%; luteolin - flowers;
• N-formyldeacetylcolchicine (antineoplastic).

Collection time: tubers - before flowering, flowers - September-November, seeds - June-July.

Collection: Colchicum corms are harvested immediately before flowering plants. They are freed from the aerial part and from the roots, cleaned from the ground and used fresh or rarely dried (cut into pieces and dried in the sun or in an oven). The output of alkaloids from their dry raw materials is reduced by 1.6-2.2 times. It is not recommended to wash corms, because this reduces the quality of raw materials. If necessary, corms are stored fresh in a cool place on shelves, laid out in a thin layer, according to list A. The shelf life of raw materials is up to 3 months. During flowering, colchicum buds and flowers are harvested. Seeds are collected during their full ripeness (June-July), dried in a warm dark place, spreading a thin layer on the fabric. The healing properties of colchicum raw materials are preserved for one year.

In order to preserve colchicum thickets, 1-2 flowering plants per 10 square meters should be left during harvesting. m thickets (it reproduces only by seeds), and re-harvesting in the same area should be carried out no earlier than after 4-5 years.

Care must be taken during assembly, drying and storage.

In the forest belt of Abkhazia, a very close species of the magnificent colchicum grows - white colchicum, sometimes recognized as a special species, Colchicum liparochiadys Woron., It is also approved for use as a medicinal raw material.

The magnificent colchicum is listed in the Red Books: Adygea, Dagestan, Krasnodar Territory, North Ossetia and the Chechen Republic.

Colchicum autumn is listed in the Red Books: Kaluga, Leningrad and Novgorod regions in Russia.

Economic purpose: widely cultivated as ornamental plant, notable for its late flowering, when in gardens and parks there are almost no bright flowering plants. In this regard, it is introduced almost everywhere in the world in the temperate zone. Bred varieties with white, pink and several shades purple. Currently, hybrids with double flowers have appeared.

The healing properties of colchicum are widely used for medicinal purposes.

Recipes for the use of colchicum in folk medicine:

• tincture of colchicum tubers for rheumatism, gout (for external use): 1 part of dry crushed tubers to 5 parts of 50% alcohol, insist in a dark place for 21 days, shaking occasionally, filter. Apply for rubbing.
• tincture for internal use: 10 g of fresh onion per 100 ml of 45% alcohol, insist in a dark place for 21 days, shaking occasionally, filter. Take 1 drop per day for up to 20 days. With good tolerance of the medicine based on Colchicum, the number of drops can be gradually increased to 10-15.
• tincture for internal and external use: 1 part seeds to 10 parts 70% alcohol, insist in a dark place for 21 days, shaking occasionally, filter. Take 15-20 drops 3 times a day for no more than 15-20 days. For external use, the tincture is applied directly to the area of ​​pain localization.

Colchicum medicines for gout and other diseases

Application: The main active ingredients of Colchicum splendid is the alkaloid colhamine (antimitotic, antitumor - leukemia, cancer of the skin, esophagus, stomach).

Colhamin is a potent antiblastic agent and is used to treat skin cancer (exophytic and endophytic forms of stages 1 and 2) and inoperable forms of esophageal cancer (especially when cancer is localized in the lower part of it), as well as stomach cancer.

In the treatment of gastric cancer and cancer of the esophagus, the combination of colhamin with sarcolysin gives good results. Colchicum-based drugs are taken orally at the same time 3 times a week. Sarcolysin is prescribed 15 mg, rarely 10-20 mg, kolhamin - 5 mg, rarely 6 mg per dose. Colhamin and sarcolysin tablets are thoroughly crushed, mixed and taken with 1-2 tablespoons of jelly so that the drugs do not digest quickly and stay longer on the surface of the tumor, exerting a prolonged local effect on it.

In case of an overdose, manifestations such as diarrhea and temporary hair loss are possible. With the appearance of blood impurities in the vomit and tarry stool, treatment is stopped and hemostatic therapy is carried out. In the course of treatment, it is periodically necessary to conduct fecal examinations for blood content.

Kolhamin is also used in the complex treatment of chronic myelogenous leukemia, papillomas of the respiratory tract, and relapses of breast and rectal cancer.

Colhamic (0.5%) ointment. The effect of the ointment on the tumor often begins 2-3 days after the start of treatment, more often after 10-12 days. Recurrent tumors that occur after radiation therapy are usually cured no earlier than 28 days. After stopping the application of colhamic ointment, aseptic dressings are applied for 10-12 days. Treatment with colhamic ointment leads to epithelialization of the skin with a good cosmetic effect.

In folk medicine, a tincture of colchicum seeds is taken orally with deforming polyarthritis as an analgesic.

Externally, a tincture of seeds and an ointment from a mixture of seeds, flowers and corms are used as painkillers for articular rheumatism and gout.

Colchicine has antitumor effects in adenofibroma of the mammary gland and desmoid, cirrhosis, and is also a non-specific anti-inflammatory agent, parasympathomimetic, sympathomimetic (sympathomimetic) and antipruritic agent, increases capillary resistance, stimulates the adrenal cortex.

In acute gouty arthritis, anti-inflammatory treatment with colchicine is performed. It is prescribed by mouth at a dose of 0.5 mg every hour or 1 mg every 2 hours, and treatment is continued until:

• there will be no relief of the patient's condition;
• there will be no adverse reactions from the gastrointestinal tract
• or - the total dose of the drug does not reach 6 mg in the absence of effect.

Colchicine is most effective if treatment is started soon after symptoms appear. In the first 12 hours of treatment, the condition improves significantly in more than 75% of patients. However, in 80% of patients, Colchicum causes adverse reactions from the gastrointestinal tract, which may occur before clinical improvement or simultaneously with it. When taken orally maximum level Plasma colchicine is reached after about 2 hours. A dose of 1 mg every 2 hours has been developed, which will reduce the accumulation of a toxic dose to a therapeutic effect. The effectiveness of this treatment regimen requires further study.

When testing the drug, it was noticed that with intravenous administration of colchicine, side effects from the gastrointestinal tract do not occur, and the patient's condition improves faster. As an initial dose, 2 mg should be administered intravenously, and then, if necessary, repeat the administration of 1 mg twice with an interval of 6 hours.

Pharmaceuticals:

• "Colhamin" ("Colchaminum"): is one of the alkaloids isolated from corms of Colchicum splendid. Apply "Kolhamin", in combination with sarcolysin, for the treatment of cancer of the esophagus.

Mode of application:"Kolhamin" is prescribed orally in the form of tablets of 6-10 mg (0.006-0.01 g) 2-3 times a day, the total dose per course is 50-100 mg. Such use of kolhamin requires careful medical supervision and control of the cellular composition of the blood.

Side effects: when taking colhamin inside, nausea and vomiting may occur. In case of an overdose, severe inhibition of hematopoiesis is possible.

Contraindications: the use of Kolhamin (and its combinations with other antitumor drugs) in esophageal cancer is contraindicated with signs of impending perforation in the bronchi and in the presence of perforation; with a pronounced inhibition of bone marrow hematopoiesis, as well as anemia (decrease in hemoglobin in the blood).

Storage conditions: list A, in a cool, dark place. Synonyms: Demecolcin, Omain, Colcemid, Demecolsin.

• "Colchicine" (Colchicin): used for acute gouty attacks and for the prevention of recurrence of gouty attacks, especially in the first 2 years after the start of taking hypouricemic drugs, with systemic scleroderma, amyloidosis, Behcet's disease, familial Mediterranean fever.

Mode of application: acute attacks of gout and acute inflammatory processes: 1 day - 1 tablet 3 times a day; 2 and 3 days - 1 tablet 2 times a day (morning and evening); Day 4 - 1 tablet in the evening. Next days- 1 tablet per day (in the evening). In chronic gout, colchicum medicine is prescribed in the amount of 1 tablet to be taken in the evening. To prevent gout attacks during hypouricemic courses of treatment: 1 tablet a day in the evening, apply for 3 months for gout without tophi. Dragee: initial dose 2 tablets, then every 1-2 hours 1-3 tablets until the pain syndrome disappears; the maximum daily dose is 16 tablets. For the prevention of exacerbation of gout, 1-3 tablets per day are prescribed daily or every other day; the duration of the course of treatment is 3 months. With a periodic illness complicated by amyloidosis, for a long time (up to 5 years or more), 1-1.5 mg per day. Side effects: dyspeptic symptoms (nausea, vomiting, anorexia, diarrhea, etc.) that occur when high doses are taken orally, myelosuppression (leukopenia, agranulocytosis, aplastic anemia, thrombocytopenia - usually with long-term treatment), temporary alopecia, liver failure, renal dysfunction, depression, myopathy, peripheral neuritis, reversible aspermia, malabsorption syndrome, manifested by vitamin B12 deficiency, skin allergic reactions, local irritation with intravenous administration and extravasation - severe pain, necrosis.

Overdose: nausea, vomiting, severe diarrhea, abdominal and oral pain, hemorrhagic gastroenteritis, skin burning, severe dehydration with hypotension and hypovolemic shock, reduced myocardial contractility and ST elevation on ECG, hematuria, oliguria, convulsions, ascending paralysis, respiratory depression . Perhaps the development of hepatocellular damage, acute renal failure, pulmonary infiltrates. 5 days after an overdose, severe bone marrow suppression with leukopenia, thrombocytopenia, and coagulopathy may occur. Treatment: carried out in a toxicological center. There is no specific antidote. Hemodialysis is ineffective. Requires airway control, assisted ventilation, monitoring and maintenance of vital functions, normalization gas composition blood, electrolyte balance, anti-shock measures.

Contraindications: hypersensitivity, lesions of the gastrointestinal tract, bone marrow, neutropenia, impaired liver and kidney function, purulent infections, cardiovascular pathology, alcoholism, pregnancy, old age.

Special instructions: a false-positive urine reaction to hemoglobin and red blood cells is possible.

• colhamic ointment 0.5% ("Unguentum Colchamini 0.5%"): yellowish mass of a rather thick consistency with a peculiar odor, with a high degree of dispersion, consisting of colhamine, emulsifier, synthomycin (the latter to prevent secondary infection) and water. Produced and stored in tightly closed jars of 25 and 100 g. Kolhamin ointment is recommended for use in exophytic and endophytic forms of skin cancer of stage I and II. There is evidence of the use of colhamic ointment in the treatment of skin warts of viral etiology. Composition: kolhamina - 0.5 g, thymol - 0.15 g, synthomycin - 0.05 g, emulsifier - 26 g, alcohol - 6 g, water - 67.3 g (per 100 g of ointment).

Mode of application: ointment in an amount of not more than 1.5 g is applied with a spatula directly to the surface of the tumor and the surrounding skin (0.5-1 cm), covered with a gauze cloth and sealed with adhesive tape. The ointment is applied daily. The course of treatment is 18-25 days. If necessary (with endophytic forms), treatment is continued for another 7-10 days. When dressing, the remnants of the previously applied ointment, decaying tumor tissue, fibrinous plaques are carefully removed, both directly from the tumor and from the surrounding skin areas. After stopping the application of the ointment, an aseptic (sterile) dressing is applied for 10-12 days and a thorough dressing of the wound is performed. At the first sign toxic action, the ointment is canceled, glucose, ascorbic acid, leukogen or other stimulants of leukopoiesis (the process of formation of leukocytes) are prescribed, if necessary, blood is transfused.

Side effects: colhamic ointment penetrates the skin and mucous membranes and in large doses can cause leukopenia (low white blood cell count), protein in the urine, diarrhea and other side effects that can occur when the drug is taken orally. When these symptoms appear, treatment with colhamic ointment is stopped, glucose with ascorbic acid, leukopoiesis stimulants (sodium nucleinate, pentoxyl, methylthiouracil, leukogen, ascorbic acid, pyridoxine, folic acid, cyanocobalamin, etc.) are prescribed, if necessary, blood substitutes are transfused.

Contraindications: the use of the ointment is contraindicated in stage III and IV skin cancer with metastases (new tumors that have appeared in other organs and tissues as a result of the transfer cancer cells with blood or lymph from the primary tumor). Do not apply colhamic ointment near mucous membranes.

Caution: all parts of the plant are highly poisonous!!!

• Colchicum preparations are contraindicated in renal and hepatic insufficiency, purulent diseases, pregnancy.
• It is not recommended to apply colhamic ointment near the mucous membranes (conjunctiva of the eyelids, mucous membrane of the oral cavity, rectum). Penetrating through the skin and mucous membranes, colchamine in large doses can cause leukopenia and other side effects that are observed with the internal use of colchamine. When using kolhamina, nausea and vomiting may occur. In case of an overdose, inhibition of the hematopoietic function is possible.
• Special precautions should be taken when administering intravenous colchicine. It has an irritating effect and, if it enters the tissues surrounding the vessel, can cause severe pain and necrosis. It is important to remember that the intravenous route of administration requires care and that the drug should be diluted in 5-10 volumes of the usual saline solution and continue infusion for at least 5 minutes.
• With diarrhea and diabetes, Colchicum is contraindicated.
• Both orally and parenterally, colchicine can depress bone marrow function and cause alopecia, liver cell failure, depression, convulsions, ascending paralysis, respiratory depression, and death. Toxic effects are more likely in patients with liver, bone marrow, or kidney disease, and in those receiving maintenance doses of colchicine. In all cases, the dose of the drug must be reduced.
• Colchicum should not be given to patients with neutropenia.
• Colchicum preparations are not prescribed for oppression of bone marrow hematopoiesis (leukocyte level below 4x109 / l, platelets below 100x10 / l), as well as anemia.
• In stage III and IV skin cancer with metastases, the use of kolhamin ointment is contraindicated.
• When an admixture of blood appears in the vomit and tarry stools, treatment is stopped and hemostatic therapy is carried out. In the course of treatment, it is necessary to conduct a study of feces for occult blood.
• Diarrhea and temporary alopecia are possible when taking colchicum.
• All parts of the plant, especially damaged bulbs, and even the water in which the flowers stood, are poisonous, and flower growers and herbalists should handle them with care, be sure to work with gloves and preferably in a medical mask.
• For home treatment, you can use herbal raw materials only for external use, observing all safety measures.

Treatment with drugs "Colhamin" and "Colchicine" is carried out in a hospital under the constant supervision of a doctor.

The alkaloid colchicine damages the microtubular apparatus of cells and stops their division. It also damages nerves and blood vessels.

Poisoning can be very severe: after a few hours, there is a burning sensation in the throat, burning of the skin, dizziness and nausea, vomiting, severe diarrhea, abdominal and oral pain, which can later turn into colic, hemorrhagic gastroenteritis, severe dehydration with hypotension and hypovolemic shock, decreased myocardial contractility, hematuria, oliguria, convulsions, ascending paralysis, respiratory depression and collapse.

There is evidence that 6 g of colchicum seeds contain lethal dose its alkaloids.

Treatment: give enveloping agents, milk, tea, tannin solutions.

• Gastric lavage in case of colchicine poisoning in most cases does not give positive results.

There is no antidote! Treatment is based on the appointment of symptomatic agents.

Calling an ambulance is required.